
UNDER-EYE POLYNUCLEOTIDES
This makes polynucleotides an excellent option for clients who are not suitable for tear trough filler, or who prefer a regenerative approach to under-eye rejuvenation.
A typical treatment plan consists of a course of 3 sessions spaced 3–4 weeks apart, with gradual improvements in skin texture and brightness developing over time. Results typically last 6–12 months, with maintenance sessions recommended.
At Derma Mayfair, all treatments are performed by a qualified doctor, ensuring safe, precise application in this delicate area.
Please note: Polynucleotides are a medical injectable treatment. A full medical and psychosocial assessment is required to determine clinical appropriateness before treatment. Treatments are only provided where there is a clear therapeutic benefit, and we reserve the right to decline treatment if it is not deemed clinically suitable.
Polynucleotides are regenerative injectables derived from purified DNA fragments. They work by stimulating cell repair, collagen production, and tissue regeneration, improving skin quality over time.
They hydrate, stimulate collagen and elastin production, and encourage skin regeneration. They also help to reduce pigmentation. This leads to smoother, firmer, and brighter under-eye skin without adding volume.
Improvements are usually seen gradually over a few weeks, with optimal results after completing a course of treatments.
Results typically last 6–12 months, depending on individual factors. Maintenance treatments can help prolong results.
No. Unlike fillers, which replace lost volume, polynucleotides work by stimulating regeneration within the skin. This makes them especially suitable for delicate under-eye skin that may not tolerate filler well.
Yes. Polynucleotides are biocompatible and widely used in medical aesthetics. As with any injectable, mild swelling, redness, or bruising may occur but usually settles quickly.
The injections are delivered with a fine needle or cannula. A numbing cream can be applied beforehand, and most clients find the treatment very tolerable.
Yes. They can be combined with tear trough filler, Profhilo, or other skin treatments to enhance overall rejuvenation. Your doctor will recommend the best plan based on your concerns and goals.
Polynucleotides are an advanced regenerative injectable treatment designed to improve skin quality, hydration, and elasticity by stimulating the body’s own repair processes. Unlike dermal fillers, which add volume, polynucleotides work at a cellular level to support long-term skin health and rejuvenation.
This makes polynucleotides an excellent option for clients who are not suitable for tear trough filler, or who prefer a regenerative approach to under-eye rejuvenation.
A typical treatment plan consists of a course of 3 sessions spaced 3–4 weeks apart, with gradual improvements in skin texture and brightness developing over time. Results typically last 6–12 months, with maintenance sessions recommended.
At Derma Mayfair, all treatments are performed by a qualified doctor, ensuring safe, precise application in this delicate area.
Please note: Polynucleotides are a medical injectable treatment. A full medical and psychosocial assessment is required to determine clinical appropriateness before treatment. Treatments are only provided where there is a clear therapeutic benefit, and we reserve the right to decline treatment if it is not deemed clinically suitable.
Polynucleotides are regenerative injectables derived from purified DNA fragments. They work by stimulating cell repair, collagen production, and tissue regeneration, improving skin quality over time.
They hydrate, stimulate collagen and elastin production, and encourage skin regeneration. They also help to reduce pigmentation. This leads to smoother, firmer, and brighter under-eye skin without adding volume.
Improvements are usually seen gradually over a few weeks, with optimal results after completing a course of treatments.
Results typically last 6–12 months, depending on individual factors. Maintenance treatments can help prolong results.
No. Unlike fillers, which replace lost volume, polynucleotides work by stimulating regeneration within the skin. This makes them especially suitable for delicate under-eye skin that may not tolerate filler well.
Yes. Polynucleotides are biocompatible and widely used in medical aesthetics. As with any injectable, mild swelling, redness, or bruising may occur but usually settles quickly.
The injections are delivered with a fine needle or cannula. A numbing cream can be applied beforehand, and most clients find the treatment very tolerable.
Yes. They can be combined with tear trough filler, Profhilo, or other skin treatments to enhance overall rejuvenation. Your doctor will recommend the best plan based on your concerns and goals.

Polynucleotide treatments smooth fine lines and crepey skin under the eyes while reducing pigmentation for a clearer, fresher look.
By improving skin quality and thickness, treatment helps reduce the appearance of dark circles caused by thin or fatigued skin.
Polynucleotides enhance elasticity, deliver deep hydration, and restore radiance — leaving the skin naturally refreshed without adding volume.
The outcome is subtle rejuvenation that brightens and revitalises while preserving your natural features.
















